Denosyl is a nutritional supplement that helps minimize a variety of liver problems in dogs and cats. It has also been shown to improve liver health and function by protecting and repairing liver cells. It is recommended to improve hepatic glutathione levels in dogs and cats. For optimal absorption, give your dog or cat Denosyl on an empty stomach, at least an hour before feeding. FELINE AND CANINE DENOSYL SD4 ADMINISTRATION GUIDE Body weight Total daily administration and tablet size Up to 12 pounds (5.5 kg) One tablet of 90 mg 13 to 34 pounds (6-15.5 kg) One tablet of 225mg 35 to 65 pounds (16 to 29.5 kg) One tablet of 425 mg 66 to 120 pounds (30 to 54.5 kg) Two tablets of 425 mg Over 120 pounds (54.5 kg +) Three tablets of 425 mg The number of tablets can be gradually reduced or may be increased at any time depending on the pet's needs.